Mesut Ozil and Emre Can both played the full 90 minutes in Arsenal and Liverpool’s goalless draw in the Premier League.
Can played in his favoured midfield position for the third game in a row after spend the whole of last season in defence.
The 21-year-old played alongside Lucas Leiva and James Milner in the centre of the park.
Can replaced Jordan Henderson who came off injured during last weekend’s victory over Bournemouth.
Ozil had a quite 90 minutes for the Gunners tonight following his staring role in the Gunners 2-1 victory over Crystal Palace in the previous round.
Kick-off: 20:00 (GMT)
Stadium: Emirates Stadium
Arsenal: Cech, Bellerin, Calum Chambers, Gabriel, Monreal, Coquelin, Cazorla, Sanchez, Mesut Özil, Ramsey, Giroud
Subs: Ospina, Gibbs, Debuchy, Arteta, Flamini, Chamberlain, Walcott
Liverpool: Mignolet, Clyne, Skrtel, Lovren, Gomez, Milner, Can, Lucas, Firmino, Coutinho, Benteke
Subs: Bogdan, Sakho, Moreno, Origi, Ings, Ibe, Rossite