Barcelona take on Roma in the Champions League Group E Match Day 5 clash at the Camp Nou.
The reigning Champions League title holders go into the game in first place with 10 points and just need a draw to secure a first placed finish in the group.
Barcelona will not be able to count on Arda Turan who is not allowed to play until January due to the FIFA transfer ban currently imposed on the club.
Roma do have fellow Turkish international Salih Uçan available to play but it is unlikely that he will be given a chance in this key game.
Barcelona will be without Douglas (wrist), Rafinha (knee), Mascherano (dead leg) while Roma are missing De Rossie (thigh).
The Italian giants will be hoping to get something from the game as third placed Bayer Leverkusen who are hot on their tails will be taking on last placed BATE.
Barcelona v Roma
Stadium: Camp Nou
Kick-Off: 19:45 GMT
Barcelona: Ter Stegen; Alves, Piqué, Vermaelen, Alba; Busquets, Sergi Roberto, Iniesta; Messi, Suárez, Neymar.
Roma: Szczęsny; Maicon, Rüdiger, Manolas, Digne; De Rossi; Florenzi, Nainggolan, Pjanić, Falqué; Džeko.