Everton will be hoping to end a six games winless streak which has seen them lose their last four games in all competitions.
The West Brom clash takes place at Goodison Park at 15:00 (GMT).
Sam Allardyce’s side suffered a heavy 4-0 defeat at the hands of Tottenham last weekend.
The Toffees are without a win in their last six games but do have a comfortable seven-point gap between themselves and the relegation zone.
Cenk Tosun will make his Goodison Park debut today and will be joined by Theo Walcott in attack.
Walcott joined the Toffees from Arsenal mid-week and will strengthen Allardyce’s attacking options.
The new look ‘Fab Four’ sees Tosun spearhead the attack with Walcott and Vlasic out wide and Sigurdsson playing a No 10 role.
Allardyce will be hoping his new look attack changes his sides fortunes as they have only scored twice in their last six games in all competitions.
Wayne Rooney and Yannick Bolasie – who both started against Spurs – have meanwhile been dropped to the bench.
Gueye and Jagielka have also been dropped to make way for Schneiderlin and Holgate.
Meanwhile, West Brom find themselves in the relegation zone with just 19 points after 23 games. The Baggies have won just one game away from home this season.
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Everton v West Brom – Confirmed lineups
Everton Lineup: Pickford, Kenny, Holgate, Williams, Martina, Schneiderlin, McCarthy, Walcott, Sigurdsson, Vlasic, Tosun
Subs: Robles, Keane, Jagielka, Bolasie, Rooney, Gueye, Niasse
West Brom Lineup: Foster, Gibbs, Evans, Rondon, Phillips, Brunt, Barry, Rodriguez, Krychowiak, Dawson, Hegazi
Subs: Myhill, Nyom, Robson-Kanu, Livermore, McClean, Mcauley, Field
