The former United stars are both expected to feature in the game. Nani is expected to start while Van Persie may make a second half appearance due to lacking match fitness.
The first leg ended in a goalless draw at the Şükrü Saracoğlu stadium. A score draw or a Fenerbahçe win would take the Süper Lig outfit through the final play-off round before the group stages.
Mehmet Topal was expected to miss the game due to injury but Pereira has included him in the squad which suggests he may recover in time for the return-leg.
The full 24 man squad is as follows:
Volkan Demirel, Fabiano Riberio, Erten Ersu, Bruno Alves, Simon Kjaer, Abdoulaye Ba, Michal Kadlec, Caner Erkin, Hasan Ali Kaldırım, Şener Özbayraklı, Raul Meireles, Josef De Souza, Mehmet Topal, Uygar Mert Zeybek, Diego Ribas, Mehmet Topuz, Alper Potuk, Miroslav Stoch, Luis Nani, Moussa Sow, Jose Fernandao ve Robin van Persie.