Fenerbahce will face Portuguese giants Braga in the Europa League Last 16 following the draw that took place in the UEFA headquarters in Nyon, Switzterland.
The Yellow Canaries knocked Lokomotiv Moscow out in the last round after recording a 4-2 victory on aggregate.
The last time Fenerbahce competed in the Europa League they reached the semi-final stage of the competition but were eventually knocked out by Benfica.
Braga knocked FC Sion out at the Round of 32 stage and are currently fourth in the Portuguese league.
Fenerbahce are currently second in the Super League and take on league leaders Besiktas next in the Istanbul derby.
The full Europa League League draw is as follows:
Fenerbahce v Braga
Valencia v Athletic Bilbao
Sparta Prague v Lazio
Shakhtar Donetsk v Anderlecht
Liverpool v Manchester United
Tottenham v Borrussia Dortmund
Basel v Sevilla
Villarreal v Bayer Leverkusen