Fenerbahçe take on Bursaspor at the Şükrü Saracoğlu stadium knowing that a win would move them three points clear of Trabzonspor at the top of the table.
The Yellow Canaries are however, coming off the back of a disappointing 3-1 home defeat against Molde in the Europa League.
Bursaspor meanwhile won their first game of the season last week against Gençlerbirliği but will need more time to settle considering they sold most key players over the summer including four transfers to Fenerbahçe.
Former Bursaspor players Şener Özbayraklı and Fernandao are expected to start while Volkan Şen and Ozan Tufan could feature at some stage.
On-loan Liverpool winger Lazar Markovic is likely to get his first start while former Manchester United striker Robin van Persie could get dropped due to lacking match fitness.
FENERBAHÇE – BURSASPOR
Stadium: Ülker Stadyumu Fenerbahçe Şükrü Saracoğlu
Referee: Barış Şimşek
Kick-off: 18:00 GMT
Fenerbahçe expected starting XI: Volkan, Şener, Alves, Kjaer, Caner, Mehmet Topal, Alper, Markovic, Van Persie, Nani, Fernandao.
Manager: Vitor Pereira
Bursaspor expected starting XI: Mert, Erdem, Serdar Aziz, Dany, Emre, Faty, Hosogai, Dzsudzsak, Jorquera, Sercan, De Sutter.
Manager: Ertuğrul Sağlam