Galatasaray have seven players on the verge of an automatic suspension if they receive a yellow card in the Süper Lig game against Mersin Idmanyurdu.
Burak Yılmaz, Fernando Muslera, Semih Kaya, Yekta Kurtuluş, Olcan Adın, Umut Bulut and Hamit Altıntop are all one booking away from suspension for the Gençlerbirliği game the following week.
Hamit Altıntop and defender Aurelian Chedjou are expected to miss the Mersin game due to injury.
Goran Pandev and Aydin Yilmaz have both been ruled out due to long term injuries.
Galatasaray have won 21 out of their 30 league games this season, drawing four and losing five.
The Turkish giants are undefeated in 18 of their last 20 matches in Süper Lig and have kept three consecutive clean sheets.
The Lions are currently first in the Süper Lig, one point ahead of second placed Fenerbahçe and two ahead of third placed Beşiktaş.
Mersin are undefeated in their last five league games but have lost every game this season played against any of the top three.