Arsenal take on Olympiakos needing a win against the Greek giants to progress to the Champions League Last 16.
The Gunners have managed to reach the Last 16 stage of the competition for the last 15 seasons in fact the last time they dropped into the European League – then the UEFA league – was back in 1999-00 where they lost to Galatasaray in the final.
Arsenal boss Arsene Wenger has a number of injury concerns going into the game including Arteta (calf), Cazorla (knee), Coquelin (knee), Rosický (knee), Sánchez (hamstring), Welbeck (knee), Wilshire (calf).
Wenger will however, be able to pick Mesut Özil who has been in the best form of his Arsenal career.
Özil is the only ethnic Turk of German origin in the Arsenal side tonight but not be alone on Match Day 6 as Hakan Çalhanoğlu is likely to start for Bayer Leverkusen against Barcelona in Group E.
Olympiakos v Arsenal
Olympiacos: Roberto; Elabdellaoui, Botía, Siovas, Masuaku; Milivojević, Kasami; Sebá, Fortounis, Pardo; Ideye.
Out: Bouchalakis (thigh)
Doubtful: Da Costa (groin), Maniatis (cruciate)
Manager: Marco Silva
Arsenal: Čech; Bellerín, Mertesacker, Koscielny, Monreal; Flamini, Ramsey; Campbell, Özil, Oxlade-Chamberlain; Giroud.
Out: Arteta (calf), Cazorla (knee), Coquelin (knee), Rosický (knee), Sánchez (hamstring), Welbeck (knee), Wilshire (calf)
Manager: Arsene Wenger