Liverpool take on Sion at the Stade Tourbillon having already booked a place in the Europa League Round of 32 and need just a draw to top the group.
Reds boss Jurgen Klopp has a number of injury concerns going into the tie with Coutinho, Gomez, Ings, Sakho and Sturridge all out injured.
Klopp is expected to rotate some of his players as a result of having already qualified but Emre Can is expected to start in central midfield having missed the 2-0 defeat against Newcastle United on the weekend due to injury.
Can has one goal and one assist in all competitions for the Reds this season and has played in his preferred midfield role since the appointment of Klopp.
Sion v Liverpool
Kick-Off: 18:00 GMT
Referee: Michael Koukoulakis (GRE)
Stadium: Stade Tourbillon
Expected Starting Line Ups
Liverpool (4-3-3): Mignolet; Randall, Lovren, Toure, Smith; Milner, Can, Rossiter; Origi, Lallana, Firmino.
Manager: Jurgen Klopp
Injuries: Coutinho, Gomez, Ings, Sakho, Sturridge
Sion: Vanins; Jagne, Zverotić, Lacroix, Rufli; Salatic, Edimilson, Mujangi Bia, Kouassi; Carlitos, Assifuah
Manager: Didier Tholot