Barcelona will be looking to extend their unbeaten run to a record 39 games against fourth placed Villarreal at the El Madrigal.
Barca boss Luis Enrique will be without midfielder Andres Iniesta who picked up a knock but Arda Turan is available and will start today alongside Ivan Rakitic and Busquets in midfield.
Turan will make his 12 start and will be hoping to extend his personal record of winning all 16 games in which he has featured for Barcelona since making his debut.
The Turkish international winger has a total of four goals and two assists in all competitions for Barca this season.
Villarreal v Barcelona
Stadium: El Madrigal
Kick-Off: 15:00 GMT
Barcelona (4-3-3): 13.Bravo 3.Piqué 4.Rakitic 5.Sergio 7.Arda 9.Suárez 10.Messi 11.Neymar Jr 14.Mascherano 18.Jordi Alba 20.Sergi Roberto
Subs: 1.Ter Stegen 6.Dani Alves 15.Bartra 17.Munir 21.Adriano 22.Aleix Vidal 24.Mathieu
Manager: Luis Enrique
Villarreal (4-4-2): Asenjo; Mario, Ruiz, Trigueros, Bailly; Rukavina, Bruno, Castillejo, Denis; Cedric, Soldado
Subs: Bonero, Adrian, Pina, Alfonso, Barbosa, Bonera, Baptistao
Manager: Marcelino García Toral