Besiktas take on Karabukspor at the Vodafone Park stadium hoping to return to winning ways after being held to a 2-2 draw against Bursaspor last week.
Fortunately for the Black Eagles, Galatasaray lost to Sivasspor, while Fenerbahce dropped points at home against Genclerbirligi and Basaksehir also drew.
The reigning Super Lig champions take on bottom-placed Karabukspor with a full strength side.
Senol Gunes has made a few changes to the side that drew to Bursaspor.
Ryan Babel returns from suspension and Gary Medel starts in defence at the expense of Vida who has been relegated to the bench.
Alvaro Negredo starts upfront with Ricardo Quaresma out wide, Babel on the other flank and Anderson Talisca playing as a No 10.
The midfield will be occupied by Atiba Hutchinson and Oguzhan Ozyakup.
Gunes has decided to start Adriano over Caner Erkin as his left-back.
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Besiktas – Karabukspor – Confirmed Line-ups
Stadium: Vodafone Park
Kick-Off: 19.00 (Local Time)
Referee: Bülent Yıldırım
Besitkas: Fabri, Gökhan, Pepe, Medel, Adriano, Atiba, Oğuzhan, Quaresma, Talisca, Babel, Alvaro Negredo
Manager: Şenol Güneş
Karabukspor: Çağlar, Hakan, Kravchenko, Ferhat, İshak, Skulason, Osman, Ergin, Ibanez, Bliznichenko, Alexe
Manager: Levent Açıkgöz
