Arsenal take on Italian giants AC Milan at the San Siro tonight in the Europa League Last 16 first-leg tie.
The North London based outfit are in poor form and have lost their last four games.
AC Milan manager Gattusso got his side back on track, the Italian giants have kept six consecutive clean sheets and are unbeaten in their last 13 games.
Wenger received more bad news heading into the game as Hector Bellerin who suffered inflammation in his knee during a training session on Wednesday morning has been ruled out.
The Arsenal boss has decided to rejig his defence after a poor run of form – and being forced to do so due to injuries.
Chambers, Koscielny, Kolasinac and Mustafi make up the back four heading int the game.
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Wenger will have star duo Henrikh Mkhitaryan and Mesut Ozil available and both start.
January transfer Pierre-Emerick Aubameyang is however, cup tied and Alexandre Lacazette is ruled out with injury as is Nacho Monreal.
With Aubameyang and Lacazette both out Danny Welbeck has ended up getting the nod upfront.
AC Milan vs Arsenal Confirmed Line-up
AC Milan (4-3-3): Donnarumma; Calabria, Romagnoli, Bonucci, Rodriguez; Bonaventura, Biglia, Kessie; Suso, Cutrone, Calhanoglu
Arsenal (4-3-3): Ospina, Chambers, Koscielny, Kolasinac, Mustafi, Xhaka, Ramsey, Wilshere, Mkhitaryan, Ozil, Welbeck
Subs: Cech, Holding, Maitland-Niles, Elneny, Iwobi, Nelson, Nketiah
