AC Milan will have to turn around a 2-0 aggregate scoreline if they want to knock Arsenal out of the Europa League at the Emirates on Thursday.
The Rossoneri find themselves in a tricky situation after losing the first-leg at the San Siro.
The defeat was their first in 13 games.
AC Milan do however, have an impressive away record, winning their last four games on the road, scoring 10 times and not conceding a single goal in the process.
The visitors have just an impressive record in Europe losing just one of their last 20 games.
The Italian giants will be without defensive duo Ignazio Abate and Davide Calabria.
“Abate has picked up a lesion at his left calf, it’s hard to predict his recovery time but he is not expected to remain out of action for long time”, AC Milan’s doctor Melegatti said.
“Calabria has been diagnosed with a muscle injury, he will remain at Milanello to undergo a medical treatment but we hope to recover him in time for Sunday’s clash.”
Donnarumma will almost certainly start in goal.
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The defence is likely to be comprised of Rodriguez, Romagnoli, Bonucci and Calabria.
Kessie, Biglia; Bonaventura are expected to feature in a three-man midfield while Suso and Calhanoglu start out wide and Cutrone could get the nod up front.
There has however, been rumors that Gattuso could switch to a 4-4-2 setup.
Predicted AC Milan lineup:
Donnarumma; Rodriguez, Romagnoli, Bonucci, Calabria; Kessie, Biglia; Bonaventura, Suso, Calhanoglu; Cutrone