Roma take on Liverpool in the Champions League semi-final first leg clash next Tuesday but face a grueling fixture list beforehand.
The Giallorossi face two games before the Liverpool clash but cannot afford to neglect the Serie A matches as they must secure top-four to guarantee Champions League football next season.
Roma take on Genoa on Wednesday and then SPAL on Saturday before traveling to England.
Il Corriere della Sera claim that Roma boss Eusebio Di Francesco is considering resting Alessandro Florenzi and Lorenzo Pellegrini today.
Per the source, Turkey international star Cengiz Under and Stephan El-Shaarawy too could be rested.
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Under only recently recovered from injury, coming on as a substitute against Barcelona in the quarter-finals second leg to provide the assist that took them through to the semi-finals.
Alternatively Under and El-Shaarway could fill in for Nainggolan and Schick.
Maxime Gonalons could be drafted in for the league games while Daniele de Rossi could also be rested.
Barcelona match-winner Kostas Manolas is also expected to miss the Genoa game out with cramps as well.
Di Francesco faces a tricky task in rotating his side while trying to win all three upcoming games in a season-defining period for the Italian manager.