Galatasaray will be hoping to return to winning ways when they take on Bundesliga giants Schalke O4 on Wednesday evening.
The clash takes place at the Turk Telekom Arena while kick-off is scheduled for 20:00 (GMT).
Make sure to scoop up any free bets ahead of the clash if you are interested in placing a wager.
Galatasaray currently sit third place in Group D with three points after two games. The Lions suffered a 1-0 defeat to FC Porto on Portugal and know they need to register a win to avoid being cut adrift.
Schalke 04 meanwhile are unbeaten so far with a win and draw over Lokomotiv Moscow and Porto.
Galatasaray were held to a 1-1 draw by Bursaspor at home on Friday and manager Fatih Terim is facing a major injury headache.
Serdar Aziz, Fernando, and Feghouli were all forced off with injuries in the first half against Bursaspor and are doubts going into the midweek clash. Meanwhile, summer signing Emre Akbaba is ruled out with a toe injury.