Galatasaray take on Bursaspor in their first Super Lig game back after the international break hoping to keep their spot at the top of the table.
The Lions are in great form at the Turk Telekom Arena winning all four home games this term.
Bursaspor meanwhile have the second worst away record in the league picking up just two points on their travels.
Galatasaray manager Fatih Terim will however, have one eye on the Champions League Match Day 3 clash against Schalke on Wednesday.
Additionally, Terim has a growing injury crisis.
Everton loanee Henry Onyekuru has been ruled out for up to six weeks with a hamstring injury.
Younes Belhanda, Garry Rodrigues and Ryan Donk could all miss the game due to injury.
Belhanda has a muscle problem and Rodrigues is recovering from a pulled hamstring.
Donk meanwhile has returned to training but may end up being rested ahead of the Schalke clash.
Badou Ndiaye is match fit and the Stoke City loanee is likely to start.
Fernando and Mariano will have to be careful as they will pick up an automatic suspension if they receive a yellow card which would rule them out of the Malatyaspor game.
Galatasaray vs Bursaspor – Probable Lineups
Stadium: Türk Telekom
Referee: Ali Palabıyık
Kick-Off: 20:00 Local Time
Galatasaray: Muslera, Mariano, Ozan, Serdar, Ömer, Fernando, Ndiaye, Sinan, Selçuk, Feghouli (Yunus Akgün), Eren.
Manager: Fatih Terim
Bursaspor: Okan, Barış, Chedjou, Ertuğrul, Latovlevici, Shehu, Ramazan, Aytaç, Umut, Stancu, Sakho.
Manager: Samet Aybaba