Galatasaray take on Real Madrid in the Champions League at the Turk Telekom Arena on Tuesday looking for their first win in Group A.
The Lions head into Match Day 3 on one point having drawn with Club Brugge on the road and suffering a 1-0 defeat against PSG at home.
Head coach Fatih Terim will be without star striker Radamel Falcao but will have in-form Brighton loanee Florin Andone as his replacement.
Terim has benched Şener, Ömer Bayram and Emre Mor despite all three impressing in the 3-2 win over Sivasspor.
The Romania international scored a brace in the victory over Sivasspor last weekend and has got the nod upfront.
Terim will start Ryan Babel on the wing with Younes Belhanda on the other flank.
The midfield trio will be comprised of Ryan Donk, Jean-Michael Seri and Steven Nzonzi.
Fernando Muslera starts in goal as expected, meanwhile, Luyindama and Marcao will be the centre-back pairing with Nagatomo and Mariano as full-backs.
Galatasaray vs Real Madrid
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Subs: Okan, Şener, Adem, Selçuk, Ömer, Feghouli, Emre Mor
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