Slaven Bilic will field a full strength squad against Partizan in the Europa League Group C.
Necip Uysal has been replaced by İsmail Köybaşı at right-back and Cenk will be filling in for the injured goalkeeper Tolga Zengin.
Bilic will have his team setup in a 4-2-3-1 formation with Atiba Hutchinson and Veli Kavlak sitting in front of the back four and Oğuzhan Özyakup pulling the creative strings in midfield.
Gökhan Töre and Olcay Şahan will start out wide with Demba Ba the main target-man upfront.
Confirmed XI
Beşiktaş: Beşiktaş: Cenk, Köybaşı, Franco, Sivok, Motta, Veli, Atiba, Oğuzhan, Töre, Olcay, Ba
Partizan: Lukac Ostojic Cirkovic Stankovic Volkov Pantic Zivkovic Markovic Stevanovic Lazovic Skuletic
In the other Group C game Mauricio Pochettino has rotated his Tottenham side but still has a number of first team players such as Eriksen, Lamela and Dembele.
Confirmed XI
Asteras Tripolis: Kosicky, Lluy, Sankare, Zisopoulos, Panteliadis, Munafo Horta, Mazza, Usero, Rolle, Tsokanis, Parra
Tottenham: Vorm, Dier, Fazio, Vertonghen, Davies, Stambouli, Dembele, Townsend, Eriksen, Lamela, Kane
