Karabukspor vs Besiktas: Confirmed Lineups – Pepe starts for the Black Eagles
Besiktas take on Karabukspor at the Dr Necmettin Seyhoglu stadium knowing the hosts have developed a reputation as giant killers.
Karabukspor beat Galatasaray and Besiktas last season.
The Black Eagles will be hoping to avoid a repeat of what happened last time they visited Karabuk.
Senol Gunes has named a strong squad with Pepe, Anderson Talisca and Babel starting.
Turkish national team hero Oguzhan Ozyakup starts but the goalscorer in the victory over Croatia, Cenk Tosun is on the bench.
Negredo will get his first start against Karabukspor.
Ricardo Quaresma meanwhile is on the bench after picking up a slight knock. Fellow star players Medel and Atiba Hutchinson also head into the game on the bench.
See More: Turkish League Previews & Predictions 4: 7 Wins 1 Loss
Karabukspor vs Besiktas: Confirmed Lineups
Stadium: Dr. Necmettin Şeyhoğlu
Referee: Ali Palabıyık
Kick-Off: 15:00 GMT
Karabukspor: Rybka, Kerim Zengin, Dany, Basdas, Papp, Gulselam, Torje, Poko, Tanase, Grozav, Yatabare
Manager: Erkan Sözeri
Besiktas: Fabri, Necip, Pepe, Tosic, Caner, Tolgay, Oguzhan, Talisca, Lens, Babel, Negredo
Manager: Şenol Güneş
Subs: Tolga, Utku, Mitrovic, Medel, Fatih, Atiba, Quaresma, Orkan, Mustafa, Cenk