Besiktas take on Malmo in their Europa League Match Day 6 clash at the Vodafone Park Stadium needing a win to book a place in the next round of the competition.
The Black Eagles could get through to the next round with a draw should Genk avoid defeat against Sarpsborg in the other Group I game.
A win would however, guarantee a place in the Round of 32.
Liverpool loanee Loris Karius has been in good form for Besiktas despite reports in the media claiming otherwise.
Karius has kept a clean sheet in his last two games for the Black Eagles including the Istanbul derby victory over rivals Galatasaray.
The German keeper is almost certain to start in goal heading into the Europa League decider.
Senol Gunes will be without Pepe, Ryan Babel, Enzo Roco, Caner Erkin and Dorukhan Toköz due to injury.
Atiba Hutchinson and Guven Yalcin meanwhile miss out as they have not been registered by UEFA.
Besiktas – Malmo Probable Lineups
Stadium: Vodafone Park
Referee: Luca Banti
Kick-Off: 20:55 Local Time
Besiktas: Karius, Gökhan, Necip, Vida, Adriano, Medel, Oğuzhan, Ljajic, Quaresma, Mustafa, Love
Manager: Şenol Güneş
Malmo: Dahlin, Bransson, Bengtsson, Nielsen, Vindheim, Rieks, Lewicki, Bacirou,Trautason, Christiansen, Rosenberg
Manager: Uwe Rösler