Manchester kick off their title defence with a tough trip to London this weekend where they will face Arsenal.
The Citizens racked up over 100 points last season and will be hoping to be the first team since Man United to win the Premier League title back to back.
City signed Algeria international Riyad Mahrez for £60 million and brought in youngsters Philippe Sandler and Daniel Arzani.
Meanwhile, Yaya Toure left the club on a free transfer.
The Citizens haven’t lost an opening game of the season since 2008/09.
Man City Team News:
Star playmaker Ilkay Gundogan is available for selection despite undergoing surgery on his noes over the summer.
The 27-year-old underwent an operation to fix a deviated septum.
Gundogan featured against Chelsea last weekend during the Community Shield Final which City won by a 2-0 scoreline.
City boss Pep Guardiola will be unable to call upon Danilo, Mangala and Sandler due to injuries while Laporte is a doubt.