Manchester United welcome Sevilla to Old Trafford for the Champions League Last 16 second-leg hoping to book a place in the quarter-finals for the first time since 2014.
The first-leg ended in a goalless draw giving United the home advantage.
Paul Pogba returns to the squad after missing the 2-1 win over Liverpool over the weekend with a thigh problem.
Pogba has however, been benched.
Antony Martial also missed the Liverpool clash and is out against Sevilla.
Jose Mourinho is facing a bit of a defensive crisis with Phil Jones, Daley Blind, and Marcos Rojo all out injured.
Marouane Fellaini made his return against Liverpool, coming on as a second-half substitute and he will start tonight.
Turkish-Football reported that Galatasaray will be keeping tabs on the Belgium international.
The Lions have been keen on the powerful midfielder since the summer.
Mourinho publically ruled out a move to Galatasaray over the transfer window but would be unable to prevent a move unless Fellaini strikes a new deal before the end of the season.
McTominay has been dropped.
Rashford has kept his place in the team after his heroics against Liverpool.
Sevilla will be without Jesus Navas due to injury, Sebastien Corchia is also out and Porto loanee Miguel Layun is ineligible.
Man United vs Sevilla – Confirmed Lineup
Man Utd Starting Lineup: De Gea, Valencia, Bailly, Smalling, Young, Matic, Fellaini, Lingard, Alexis, Rashford, Lukaku
Subs: Romero, Darmian, Lindelof, Mata, McTominay, Pogba, Martial
Probable Sevilla Starting Lineup: Rico; Mercado, Kjaer, Lenglet, Escudero; N’Zonzi, Banega; Sarabia, Vazquez, Correa; Muriel