Manchester United 4-3-3 v Anderlecht: Confirmed line-ups
Manchester United take on Anderlecht in the Europa League quarter-final second leg tie at Old Trafford.
The winner of the game could go onto face Besiktas if they find a way past Lyon in Istanbul.
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Alternatively Celta Vigo, Schalke, Genk and Ajax all have the chance of booking a place in the semi-finals.
United drew the first-leg 1-1 but have a great record against Anderlecht winning all three of their previous home games against the Belgium side.
Jose Mourinho has set his side up with a 4-3-3 formation and made five changes to the side that beat Chelsea bringing in Romero, Shaw, Carrick, Mkhitaryan and Ibrahimovic.
Wayne Rooney has also returned to the starting to team after recovering from injury but has been benched.
The Red Devils actually played Anderlecht in their first European competition game, winning 10-0 in 1956 – the Belgium sides heaviest defeat in UEFA competition.
Anderlecht have failed in win in England in 15 attempts, drawing two and losing 13.
Manchester United 4-3-3 v Anderlecht: Confirmed line-ups
Manchester United: Romero, Valencia, Bailly, Rojo, Shaw, Carrick, Pogba, Rashford, Mkhitaryan, Lingard, Ibrahimovic
Anderlecht: Martinez, Appiah, Kara, Spajic, Obradovic, Dendoncker, Tielemans, Acheampong, Chipcui, Hanni, Teodorczyk