Besiktas take on Kasimpasa knowing that a victory will take them seven points clear – with a game in hand – over second placed Fenerbahce.
Kasimpasa could be without on-loan Chelsea defender Kenneth Omeruo who missed the international break for Nigeria due to injury.
Omeruo has recovered but the manager will make a game time decision wether he will start or not. The 21-year-old has been a key figure in the Kasimpasa defence this season and his absence would be sorely missed against the leagues most potent attack.
Besiktas have a few key players out as well including the injured Rhodolfo and Gökhan Töre while Ricardo Quaresma is suspended.
The Black Eagles are in great form and have an impressive record away to Kasimpasa having won their last four games on the road against the Istanbul minnows.
Kasimpasa v Besiktas
Stadium: Recep Tayyip Erdogan
Kick-Off: 18:00 GMT
Kasımpaşa: Isaksson, Bozhikov, Titi, Veigneau, Popov, Scarione, Del Valle, Hakan, Abdullah, Adem, Eren Derdiyok
Manager: Riza Calimbay
Beşiktaş: Tolga (Boyko), Beck, Marcelo, Delgado, İsmail, Atiba, Sosa, Oğuzhan, Olcay, Kerim, Gomez
Manager: Senol Gunes