Besiktas take on Napoli at the San Paulo stadium looking for their first Champions League win after drawing their first two games.
Black Eagles boss Senol Gunes has made a few surprise changes. Adriano will be played as a left-winger despite being a left-back, Necip will start ahead of Gokhan Inler who failed to recover from injury in central midfield and Tolgay Arslan got the nod ahead of Anderson Talisca.
Star midfielder Oguzhan Ozyakup has been ruled out with injury but Talisca was expected to fill in but Arslan will be the Eagles first choice attacking midfielder going into the Napoli clash.
Napoli meanwhile are without Raul Albiold and Milik due to injury.
Besiktas go into the clash having scored at least one goal in 17 of their last 18 games in European competition – a total of 23 goals – but have never beat an Italian side in Europe or managed to keep a clean sheet. Napoli meanwhile have never lost a home game in the Champions League.
Besiktas starting line-up: Fabricio, Tosic, Marcelo, Caner, Beck, Necip, Atiba, Tolgay, Adriano, Quaresma, Aboubakar
Subs: Tolga, Rhodolfo, Gonul, Inler, Olcay Sahan, Anderson Talisca, Cenk Tosun
Napoli starting line-up: Reina, Maggio, Chirches, Coulibaly, Ghoulam, Zielinski, Jorginho, Hamsik, Callejon, Mertens, Insige
Subs: Hysaj, Giaccherini, Allan, Maksimovic, Gabbiadini, Diawara, Sarri