Besiktas take on Hapoel Beer-Sheva knowing that if avoiding defeat by a two goal margin would be enough to see them book a place in the Europa League Last 16.
Black Eagles boss Senol Gunes has decided to rotate his midfielder replacing Atiba Hutchinson with Gokhan Inler and Oguzhan Ozyakup with Necip Uysal.
The attacking-midfield will remain the same as last week with Quaresma, Talisca and Babel all in the starting line-up.
Meanwhile, Vincent Aboubakar will start ahead of Cenk Tosun who has been on fire this season.
Adriano will be rested and Andreas Beck who returns from suspension will start as left-back while Dusko Tosic will start on the right.
Besiktas beat Hapoel 3-1 away from home in the first-leg and go into the return tie as firm favourites to progress to the next round.
BEŞİKTAŞ – HAPOEL BEER-SHEVA
STAT: Vodafone Arena
HAKEM: Matej Jug (Slovenya)
SAAT: 21.00
BEŞİKTAŞ: Fabri, Beck, Marcelo, Atınç, Tosic, Gökhan İnler, Necip, Quaresma, Talisca, Babel, Aboubakar
MANAGER: Şenol Güneş
HAPOEL BEER-SHEVA: Goresh, Turjman, Tzedek, Ghadir, Nwakaeme, Hoban, Ben Sahar, Broun, Ohayon, Soares, John Ogu
MANAGER: Barak Bakhar