Besiktas take on Galatasaray at the Turk Telekom Arena stadium in the Super Lig on Saturday.
The Black Eagles could be crowned champions if they end up beating the Lions.
The Black-Whites head into the derby as league leaders, five points ahead of second-placed Fenerbahce and six points ahead of third-placed Galatasaray with just three games remaining.
Besiktas will lift the title today if they beat Galatasaray and if Fenerbahce lose their respective game against Ankaragucu.
The Lions meanwhile, will be knocked out of the title race if they lose tonight.
Besiktas head into the clash in great form having won their last three league games, culminating with a 7-0 victory over Hatayspor last week.
Galatasaray meanwhile, have also hit form winning their last three games.
Besiktas will be missing Vincent Aboubakar, Cenk Tosun, Oguzhan Ozyakup and Ajidin Hasic heading into tonight’s match.
Galatasaray are without Henry Onyekuru, Fatih Ozturk, Christian Luyindama and Valentine Ozornwafor.
Galatasaray vs Besiktas Probable Lineups
Galatasaray: Muslera, Linnes (Şener), Donk, Marcao, Ömer, Taylan, Gedson Fernandes, Emre Akbaba, Emre Kılınç (Babel), Kerem, Halil
Besiktas: Ersin, Rosier, Vida, Welinton, Nsakala, Josef, Atiba, Ljajic, Ghezzal, Gökhan Töre, Larin