Besiktas take on rivals Bursaspor in the opening Super Lig game of the week at the Timsah Arena stadium.
The Black Eagles will be without the injured Dusko Tosic and Atiba Hutchinson. Ryan Babel meanwhile is suspended against the Green Crocoiles.
Gokhan Tore and Atinc Nukan fail the make the squad due to lacking match fitness.
Bursaspor meanwhile are without Jorquera, Sercan Yildirim, Emre Tasdemir, Pablo Batalla and Mikel Agu.
Anderson Talisca is available and will be hoping to add to his five goals in three games since returning from the winter break.
Pepe is expected to return after being rested for the Turkish Cup mid-week clash against Genclerbirligi.
Alvara Negredo is likely to keep his place upfront but Vagner Love will be available to make his debut.
The reigning Super Lig champions are currently six points behind league leaders Basaksehir.
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Bursaspor vs Besiktas – Probable Line ups
Bursaspor: Harun, Shehu, Ekong, Titi, Barış, Aziz Behich, Badu, Yusuf Erdoğan, Kembo, Stancu, Sow
Beşiktaş: Fabri, Gökhan Gönül, Pepe, Vida, Adriano, Medel, Tolgay, Quaresma, Talisca, Lens, Negredo