Fenerbahce take on Antalyaspor at the Sukru Saracoglu in desperate need of a victory to remain in the title race.
The Istanbul giants are currently six points behind league leaders Galatasaray but have a game in hand and will close the gap to three points with a win.
Tottenham striker Vincent Janssen is expected to make first appearance since picking up a toe injury back in December.
Janssen was expected to miss the rest of the season but could be set for his first game in four months.
The Dutch star has made the match-day squad and will be on the bench heading into the game due to not completely match fit.
The 24-year-old is likely to receive playing time against the Scorpions.
Antalyaspor are all but safe after a run of four matches without a loss.
Fenerbahce will still be favorites at home and are undefeated in 20 of their last 22 league games however, Antalyaspor have won three of their last four games against the home side.
Additionally, their manager Hamza Hamzaoglu is a former Galatasaray player and manager so he will be keen on getting one up on his former rivals.
Fenerbahce are missing Alper Potuk through injury but have no other concerns heading into the game.
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Fenerbahce – Antalyaspor: Confirmed Lineup
Stadium: Sukru Saracoglu
Referee: Yaşar Kemal Uğurlu
Kick-Off: 18:00
Fenerbahce: Volkan – Şener- Skrtel – Neustadter – Hasan Ali – Mehmet Topal – Josef – Aatif – Dirar – Giuliano – Soldado
Manager: Aykut Kocaman
Antalyaspor: Boffin, Celustka, Djourou, Diego, Sakıb, Yekta, Charles, Hakan, Maicon, Sangare, Doukara
Manager: Hamza Hamzaoğlu